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Outcomes of Transaortic Edge-to-Edge Repair of the Mitral Valve in Patients
Undergoing Minimally Invasive Aortic Valve Replacement
Christos G. Mihos, Orlando Santana, Juan C. Brenes, M.D, Joseph Lamelas, M.D.
Mount Sinai Heart Institute, Miami Beach, FL, USA.
OBJECTIVE: We evaluated the safety and durability of a transaortic edge-to-edge mitral valve repair in patients undergoing minimally invasive aortic valve replacement
METHODS:
We retrospectively analyzed all patients who underwent concomitant aortic valve replacement and transaortic edge-to-edge mitral valve repair via a right mini-thoracotomy (minimally invasive) at our institution between September 2008 and September 2011. Intra-operative transesophageal, and follow-up transthoracic echocardiograms were performed to evaluate the adequacy of the repair, and assess for any post-operative recurrence of mitral regurgitation (MR).
RESULTS: There were 24 patients identified (16 males and 8 females), with 8 patients having a history of prior heart surgery. The median EuroSCORE was 12.5 (IQR 6-23). The mitral valve lesion was classified as functional (n=11), degenerative calcification (n=10), or rheumatic (n=3). The median aortic cross clamp and cardiopulmonary bypass times were 101 minutes (IQR 86-116) and 127 minutes (IQR 109-149), respectively. There was one (4%) in-hospital death. The median total hospital length of stay was 8 days (IQR 7-12). Median pre-operative versus post-operative MR grade was 3 (IQR 3-4) versus 0 (IQR 0-1), P<0.001. Median time to follow-up echocardiogram was 13 days (IQR 5-93). Median preoperative versus follow-up MR grade was 3 (IQR 3-4) versus 1 (IQR 0-2), P<0.001, and postoperative versus follow-up MR was 0 (IQR 0-1) versus 1 (IQR 0-2), P=0.01, respectively.
CONCLUSIONS: : In patients undergoing minimally invasive aortic valve replacement with at least moderate mitral valve regurgitation, a transaortic edge-to-edge mitral valve repair is a safe and effective alternative to conventional double valve surgery
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