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Transfemoral Vs. Transapical Tavi: Single Center Experience In Kyiv
Glib Iemets, Oleksandra Telehuzova;
Ukrainian Children's Cardiac Center, Kyiv, Ukraine
BACKGROUND: This study sought to describe the 7-year pathway of TAVI in Ukraine and current impact of martial law. The aim is to compare two TAVI procedure approaches in a single center experience: transapical and transfemoral.
METHODS: We have started the TAVI program in 2016 with the manufacturing of the first Ukrainian valve. Since the war beginning a great amount of elderly people are unable to leave their homeland to find the safest place, thus the need in TAVI procedures still staying high. Physicians keep working forasmuch the operations even during air raids, an ICU located in a bomb shelter and other conditions occurred in the martial law. We pooled patient-level databases derived from the single-center multistage studies.
RESULTS: Between February 2017 and November 2023, in total, 84 TAVI patients with a mean follow-up of 900 days were enrolled in this prospective observational cohort study; 41 patients underwent transapical TAVI with Ukrainian valve and 43 patients with other valves for transfemoral approach. Safety-related adverse events were adjudicated to valvular academic research consortium-2 definitions. The mean age of our TAVI patients was (78.8± 8.7 yrs, 45.2% male, EuroSCORE II 9.6±6.3, STS Score 23.4±15.9). We assessed and compared 30-day rates of all-cause death, cerebral complications, major adverse cardiac events (MACE) and infectious complications between two groups. Clinical and angiographic predictors of MACE at 30 days were identified by Cox regression analysis. Additionally, we observed similar outcomes through two groups before and during war performed operations. The level of complication is low (< 5%). The frequency of 30-day mortality, TAVI-specific complications such as moderate/severe paravalvular leakage, major vascular, major bleeding and acute kidney injury were similar in study groups.Stroke rate and ICU length of stay were different in two groups.
CONCLUSIONS: Despite the war we are continuing to develop TAVI procedures in Ukraine, using both transapical and transfemoral approaches. Effective reorganization of cardiac surgery service due to the war allowed to maintain the quality of TAVI procedures.
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