Clinical And Echocardiographic Follow-up In Patiens With Sutureless Perceval Bioprosthesis: Single Center Analysis In 11 Years Experience
Giovanni Concistrč, Giacomo Bianchi, Rafik Margaryan, Edoardo zancanaro, Francesca Chiaramonti, Enkel Kallushi, Tommaso Gasbarri, Michele Murzi, Pierandrea Farneti, Marco Solinas.
Ospedale del cuore "G. Pasquinucci", Massa, Italy.
BACKGROUND:
We describe long-term clinical and echocardiographic follow-up in the largest single center cohort of patients underwent aortic valve replacement (AVR) with sutureless Perceval (CorCym, Italy) bioprosthesis. METHODS:
Between March 2011 and September 2022, 1237 patients underwent AVR with Perceval bioprosthesis implantation. Mean age was 78 ± 4 years and mean EuroSCORE II was 6.9 ± 2.8%. Concomitant procedures were performed in 272 patients (22%).
RESULTS: Thirty-day mortality was 1.37% (17/1237). 890 of 951 (93.5%) isolated AVR underwent minimally invasive surgery with a ministernotomy (n = 221) or right minithoracotomy (n = 669) approach. Cardiopulmonary bypass and aortic cross-clamp times were 80.6 ± 21.5 and 50.1 ± 10.5 minutes for isolated AVR and 145.8 ± 33.6 and 95.8 ± 20.7 minutes for combined procedures. At mean follow-up of 55.09 ± 6.7 months (range: 1-138.5 months), survival was 95.4% and mean transvalvular pressure gradient was 13.3 ± 4.2 mmHg. LV mass decreased from 153.5 g/m2 to 114.6 g/m2 (p< 0.001) and moderate paravalvular leakage occurred in 3 patients without hemolysis not requiring any treatment. Freedom from reoperation was 97.4%. Nine patients required surgical reintervention and 21 patients transcatheter valve-in-valve procedure for structural prosthesis degeneration at mean of 6.3 years after first operation (range: 2-10 years).
CONCLUSIONS: AVR with Perceval bioprosthesis is associated with good clinical results and excellent hemodynamic performance in our eleven-years experience. Structural degeneration rate of Perceval is comparable with others bioprosthetic aortic valve. Sutureless technology may reduce operative time especially in combined procedures and enable minimally invasive AVR.
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