Quality Of Life (qol) In Nsclc Patients Underwent Robotic Vs Open Major Resections
Gaetano Romano1, Carmelina C. Zirafa2, Ilenia Cavaliere1, Vittorio Aprile1, Sara Ricciardi1, Diana Bacchin1, Elisa Sicolo1, Federico Davini2, Franca M.A Melfi2.
1Department of Surgical, Medical, Molecular and Critical Pathology, University Hospital, Pisa, Italy, 2Multispecialty Centre for Surgery, Minimally Invasive and Robotic Thoracic Surgery, University Hospital, Pisa, Italy.
BACKGROUND To compare the short and medium term QoL in NSCLC patients underwent anatomical resections by using robotic surgery vs open surgery.
METHODS From January to June 2017 50 patients (pts) underwent lobectomy for NSCLC. In 25 of them (19 males, 6 females, mean age 67,3 years, range 46-82) was performed a lobectomy by thoracotomy and in 25 (13 males, 12 females, mean age 66,6 years, range 43-83) a robotic lobectomy. The QoL was evaluated by submitting the SF-12 questionnaire at 15 days and at 3 months after surgery. The questionnaire includes 12 questions aimed at investigating eight different scales: physical activity, physical health, emotional state, mental health, physical pain, general health, vitality, social activities. These scales are summarized in two indexes: the Physical domain (Physical Component Summary PCS-12) and the mental domain of health (Mental Component Summary MCS-12). The “Statistics” program has been used for the statistical calculation of the data and the “SF-12 calculator” for the review of the scores. The results were considered statistically significant only with a p-value of the T-test <0.05.
RESULTS The mean scores for the two synthetic indexes obtained in the open surgery group from the calculation of the SF-12 questionnaire were at 15 days: PCS 32.1360 (SD ± 5.53909); MCS 40.2440 (DS ± 10.30360), at 90 days: PCS 36.06 (DS ± 5.672); MCS 40.5880 (DS ± 8.01906). In the robotic group the mean scores resulted in: at 15 days: PCS 37.4440 (DS ± 6.72118); MCS 33.0680 (DS ± 10.43099), at 90 days: PCS 43,57 (DS ± 7.219); MCS 37.3333 (DS ± 7.24385). Our results showed a statistically significant difference in PCS at short and medium term in favor of robotic surgery. We found a statistically significant difference in short-term MCS in favor of open surgery, with similar results regarding medium-term data.
CONCLUSIONS Robotic surgery is associated with better outcomes in the Physical domain, guaranteeing a better post-operative quality of life in NSCLC patients. 
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