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Aortic Valve Replacement after Previous Heart Surgery in High Risk Patients: Transapical Aortic Valve Implantation versus Conventional Aortic Valve Replacement
Maximilian Scherner, Navid Madershahian, Elisabeth Stoeger, Parwis Rahmanian, Elmar Kuhn, Yeong Choi, Jens Wippermann, Thorsten Wahlers.
University Hospital of Cologne, Heartcentre, Cologne, Germany.
Background: Cardiac reoperations are associated with increased morbidity and mortality compared to first-time surgery. We analyzed our experience with reoperative aortic valve replacement (Redo-AVR) to assess the outcome of conventional Redo-AVR and to compare these results to patients who underwent Transapical aortic valve implantation (TA-AVI) as a second heart operation.
Methods: The review of our databases identified 91 patients with prior cardiac surgery who underwent Redo conventional AVR (n=59; since 2006) or TA-AVI (n=32; since 2008). We used the existing data for this retrospective single centre analysis.
Results: Both groups did not significantly differ in their risk profile leading to similar STS-Scores (STS-ROM: Redo-AVR: 17,9±9,9 vs. TA-AVI 20,7±8,1; p=0,174). Overall mortality was 22% (13 patients) in the Redo-AVR group and 37,5% (12 patients) after TA-AVI (p=0,142). Mean survival after Redo-AVR was 25,3±17,4 vs. 11,2±10,3 months in TA-AVI patients (p=0,053). Six-months and 18-months actuarial survival were 84,1±4,9% and 80±5,4% in the Redo-AVR group vs. 77,7±8,1% and 47,5±11,9% in TA-AVI. Multivariable analysis identified preoperative atrial fibrillation (Hazard ratio (HR) 3,12; 95% CI: 1,2-8,2; p=0,021), preoperative renal insufficiency (HR 3,26; 95% CI: 1,21-8,77; p=0,02), postoperative increase of serum creatinine >200% within 48 hours and postoperative pacemaker implantation (HR 4,3; 95% CI: 1,25-14,78, p=0,021) as independent negative predictors of long-term survival.
Conclusion: Conventional Redo-AVR can be performed with acceptable results in this population and still serves as gold standard for Redo-AVR. Reoperative isolated valve surgery via TA-AVI is feasible and results in short- and long-term survival that is comparable to patients after conventional AVR.
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