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Outcomes of Aortic Valve Replacement via Right Mini-Thoracotomy versus Median Sternotomy in Patients with Previous Coronary Artery Bypass Graft Surgery
Andres M. Pineda, M.D, Orlando Santana, M.D, Javier Reyna, M.D, Alejandro Sarria, M.D, Gervasio Lamas, M.D, Joseph Lamelas, M.D.
Mount Sinai Heart Institute, Miami Beach, FL, USA.

OBJECTIVE:
We sought to determine the safety and efficacy of a minimally invasive right mini thoracotomy for aortic valve replacement (AVR) in patients with a previous coronary artery bypass grafting (CABG) surgery.
METHODS
We retrospectively reviewed 3436 consecutive cases from January 2005 to September 2011 to identify patients with a previous CABG surgery who subsequently underwent AVR. The outcomes of those who had minimally invasive surgery were compared with those who had a median sternotomy.
RESULTS:
Fifty-two patients were identified, of which, 28 (54%) underwent a minimally invasive approach, while 24 (46%) had a median sternotomy. The minimally invasive group consisted of 28 (100%) males, with a mean age of 76.9 ± 8.1 years, while the median sternotomy group consisted of 21 (88%) males with a mean age of 75.7 ± 6.4 years, p=0.09, p=0.38, respectively. Patients in the median sternotomy group had more diabetes mellitus (68 vs. 92%, p=0.04). Other baseline characteristics, including STS score for mortality, pre-operative creatinine, ejection fraction, hypertension, and chronic obstructive pulmonary disease, were similar in both groups.
The median aortic cross clamp (85 vs. 56 minutes, p<0.001) and cardiopulmonary bypass times (132 vs. 86 minutes, p<0.001) were longer in the minimally invasive group. One patient (3.6%) in the minimally invasive group required conversion to full re-sternotomy. The mean intensive care unit (49 vs. 69 hours, p=0.12) and total hospital length of stay (8 vs. 8, p=0.47) were similar in both groups. Fewer patients in the minimally invasive required PRBC transfusion (75 vs. 100%, p=0.009).
Composite post-operative complications occurred in 4 (14%) versus 10 (42%), p=0.03, in the minimally invasive versus the median sternotomy group. The difference in composite complications was driven by lower incidence of prolonged ventilation (7.1 vs. 38%, p=0.009) and bleeding requiring reoperation (0 vs. 13%, p=0.09) in the minimally invasive group. There was no difference in the incidence of post-operative renal failure, stroke, deep wound infection, re-intubation, or in-hospital mortality.
CONCLUSIONS:
Minimally invasive AVR via a right mini-thoracotomy in patients with previous CABG surgery can be performed safely, and may be associated with decreased post-operative complications when compared with full re-sternotomy.


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