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Surgical procedures for complicated chronic Stanford Type B aortic dissection.
Michal Nozdrzykowski, Jens Garbade, Christian Etz, Ardawan Rastan, Martin Misfeld, Michael Borger, Friedrich Wilhelm Mohr.
Heart Center Leipzig, Leipzig, Germany.

Background: Chronic complicated Stanford type B dissection is associated with significant mortality and morbidity. We reviewed our experience with surgery for complicated type B dissection to determine surgical outcomes in the era of thoracic endovascular aortic repair (TEVAR).
Methods: From January 2000 to May 2010, 90 patients with chronic type B dissection were evaluated at our institution. Of there, 22 patients (14 male, mean age 61.2±8.2 years) underwent surgical repair. Five patients (23%) had previous aortic surgery (4 after previous ascending/root surgery; one after aortic coarctation repair). Indications for surgery were diameter increase to 59±4mm (n=12), covered rupture (n=1), free rupture (n=2) and failed or complicated TEVAR (n=7; after a median interval of 15 months, range: 4.5-54).
Results: Hospital mortality was 13.5% (one after previous TEVAR, two after primary surgical repair). Neurologic complications occurred in five patients: three patients developed strokes (two after prior TEVAR), one immediate paraplegia (after primary surgery) and one patient monoplegia (after primary surgery). Two patients required permanent haemodialysis (one after previous TEVAR). Seven patients required tracheotomy for respiratory failure. One-year survival was 88%. At a median follow-up of 16 months (range: 2.5-77), sixteen patients (84%) were alive and had required no aortic reintervention.
Conclusions: Open surgical repair remains the benchmark for patients with chronic complicated type B dissection in term of mortality, morbidity and survival. Surgery for complicated TEVAR can be carried out with acceptable outcome.
Table 1. Preoperative Baseline Characteristics of 22 Patients Operated on for Chronic Type B Aortic
Conservative
(n = 15)
Conservative
(n = 15)
P value
Age - years62 (54 - 69)61 (53 - 66)0.490
Female sex5 (33.3%)3 (42.9%)1.000
CHD2 (13.3%)2 (28.6%)0.565
Marfan´s Syndrome2 (13.3%)01.000
COPD2 (13.3%)3 (42.9%)0.274
Renal insufficiency4 (26.7%)3 (42.9%)0.630
Previous neurologic dysfunction
Preoperative paraplegia
Stroke
0
2 (13.3%)
2 (28.6%)
0
0.091
1.000
Urgent/emergent operation3 (20.0%)2 (28.6%)1.000
Obesity6 (40.0%)7 (100%)0.017


Table 2 Mortality after a median follow-up of 16 months (range: 2.5-77)
MortalityConservative (n=15)Prior TEVAR (n=7)P value
Hospital13.3 % (2)14.3% (1)
1-year20.0 % (3)14.3% (1)
3- years26.7 % (4)14.3% (1)0.482


Table 3 Postoperative Details and Complications
Conservative
(n = 15)
Prior TEVAR (n = 7)P value
Neurological complications
- Paraplegia early
- Paraplegia late
- Stroke
1 (6.7%)
1 (6.7%)
2 (13.3%)
0
0
2 (28.6%)
0.565
Renal insufficiency
- Creatinin > 1.5 mg/dl
- Temporary HD
- Permanent HD
5 (33.3%)
2 (13.3%)
1 (6.7%)
5 (71.4%)
3 (42.9%)
1 (14.3%)
0.172
0.274
1.000
Respiratory complications - Tracheostomy5 (33.3%)2 (28.6%)1.000
Cardiac complications
- Cardiac arrest
- Pacemaker
1 (6.7%)
1 (6.7%)
1 (14.3%)
1 (14.3%)
1.000
1.000
Sepsis2 (13.3%)1 (14.3%)1.000
MODS01 (14.3%)0.318


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