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OBJECTIVE: The preoperative characteristics and the postoperative outcome of women undergoing OCAP bypass have been in the past investigated with different outcomes. Our study was undertaken to evaluate the preoperative characteristics and postoperative outcome of women undergoing OPCAB surgery compared to men in Switzerland.
METHODS: The data of all patients who underwent off OPCAB between 1/2005-12/2010 was analysed. The preoperative characteristics and postoperative outcome of women compared to men were evaluated.
RESULTS: 885 patients underwent OPCAB between 1/2005-12/2010. 17.8% were female. There were no difference in gender with regard to COPD, diabetes and angina pectoris grading, critical preoperative state, number of diseased vessels, left main disease. Women were older(p=0.000), more obese(p=0.004), had lower preoperative haematocrit values(p=0.000), higher preoperative C- reactive protein values(p=0.11) and more likely to present with NYHA III-IV symptoms (p=0.000), higher BNP(0.001), higher ejection fraction(p=0.07), positive family history for coronary disease (p=0.18) and history for hypertension(p=0.000). Women were less likely to have undergone percutaneous intervention(p=0.024) and to have a history of smoking (p=0.000). There was no gender difference in the postoperative outcome with regard to troponin, atrial fibrillation, death and intensive care unit days. Females were intubated (p=0.001) and hospitalized longer (p=0.001) and were more likely to receive blood transfusions(p=0.000). Female gender was found to be an independent risk factor for postoperative transfusions taking in account all other variables including preoperative haematocrit (p=0.000).
CONCLUSIONS: Women in Switzerland undergoing off pump coronary bypass surgery are older and have higher BNP, CRP and NYHA grading for dyspnoea, more likely to have hypertension, positive family history and less likely to have undergone percutaneous intervention compared to males. Female gender was also found to be an independent risk for postoperative blood transfusion.