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OBJECTIVE: Usage of venovenous extracorporeal membrane oxygenation (VV ECMO) for the patients with respiratory failure has been increasing. Time criteria for the weaning of ECMO has not established. The aim of this study is to analyze time factors influencing the results of VV ECMO in the patients with respiratory failure.
METHODS: From June 2007 to July 2011, 14 cases of VV ECMO were applied in 13 patients at the time of respiratory failure. Male patients were 11 (78.6 %), and female 3. Mean age was 53.61 ± 22.31 (range: 19 - 84) years old. Factors such as demographic data, results of arterial blood gas analysis in pre- and post-ECMO, as well as during the application of ECMO, flow rate of ECMO, number of change of oxygenator, parameters during ventilator therapy are reviewed, analyze, and calculated.
RESULTS: The application of ECMO was done at in intensive care unit in 9 cases, operating room in 3, emergency room in 2. Mean duration of application of ECMO was 117.82 ± 101.51 (range: 14.1 - 306.05) hours. Successful weaning of VV ECMO was achieved in 10 cases out of 14 (71.43%). Survival discharge was 6 patients out of 14 (42.6 %). In the groups for the duration more than 48 hours of ECMO, successful weaning rate was 66.7 % (6 out of 9 cases) with 33.3 % of survival discharge. For more than average duration, 117.8 hours, the successful weaning was in 4 out of 6 cases (66.7 %) with survivial rate 50 %. 3 cases of traumatic etiology in 2 patients weaned successfully and discharged.
CONCLUSIONS: Support for more than 48 hours may enhance the chance of survival in the patients with respiratory failure. Application of VV ECMO for traumatic patients shows good results of weaning rate and survival.