Influence of cardiac surgery on electromagnetic QRS fragmentation index in patients undergoing elective on-pump cardiac surgery due to Aortic Valve or Coronary Artery disease?
Inna Kammerer, Helena Garcia Jordan, Thomas Kleemann, Ralf Zahn, Falk-Udo Sack.
Academic City Hospital Ludwigshafen, Ludwisghafen, Germany.
OBJECTIVE: High-resolution magnetocardiography with electromagnetic QRS fragmentation is suggested to have the propensity to detect myocardial ischemia, arrhythmic events and increased mortality in postmyocardial infarction (MI) with left ventricular dysfunction. Aim of our prospective study was to compare the electromagnetic QRS fragmentation index (eQFI) in elective cardiac patients before and after undergoing cardiac surgery.
METHODS: A prospective study (03-09/2012) was performed in 35 patients (66 years, 65% male, 9% with EF 30-50%) undergoing elective coronary artery bypass graft (CABG, n=23) or aortic valve replacement (AVR, n=12) at the Heart Center Ludwigshafen, Germany. The measurement of eQFI was done before and 7 days after extracorporeal circulation. A QRS fragmentation index > 1.2 was defined as an increased eQFI and an eQFI change of > 0.1 before and after intervention as a significant change.
RESULTS: The mean ischemia time accounted 47+17min. The demographic dates of elective cardiac surgery patients undergoing CABG or AVR were not significantly different. No hospital death was observed. The comparison of eQFI did not show significant differences before and 1 week after the cardiac procedure: 1.07 + 0.386 vs. 1.06 + 0.267 without differences in both groups.
CONCLUSIONS: Our study could not show an acute effect of cardiac surgery on the eQFI. Further eQFI measurements are needed to evaluate if an effect of cardiac surgery can be observed during a longer follow-up period.
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